INFECTION EXPERIMENTS WITH NOVEL PISCINE ORTHOREOVIRUS FROM RAINBOW TROUT (ONCORHYNCHUS MYKISS) IN SALMONIDS.

Infection experiments with novel Piscine orthoreovirus from rainbow trout (Oncorhynchus mykiss) in salmonids.

A new disease in farmed rainbow trout (Onchorhyncus mykiss) was described in Norway in 2013.The disease mainly affected the heart and resembled heart and skeletal muscle inflammation (HSMI) in Atlantic salmon (Salmo salar L.).HSMI is associated with Piscine orthoreovirus (PRV), and a search for a similar virus in the diseased rainbow trout led to d

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Spermatogenic cell-specific type 1 hexokinase (HK1S) is essential for capacitation-associated increase in tyrosine phosphorylation and male fertility in mice.

Hexokinase (HK) catalyzes the first irreversible rate-limiting step in glycolysis that converts glucose to glucose-6-phosphate.HK1 is ubiquitously expressed in the brain, erythrocytes, and other tissues where glycolysis serves as the major source of ATP production.Spermatogenic cell-specific type 1 hexokinase (HK1S) is expressed in sperm but its ph

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